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Jak/Stat: IL-6 receptor family
The JAK–STAT pathway is a direct route from cytokine receptors to gene transcription. For the IL-6 cytokine family, which signals through the […]
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Cell cycle/Checkpoint
Cell cycle control: G1/S checkpoint. G2/M damage checkpoint.
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Translational control
Translational control: mTOR. Translational control overview. Regulation of elF4E and p70 S6K. Regulation of elF2.
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Apoptosis signaling
Apoptosis signaling pathways: Regulation of Apoptosis Overview. Inhibition of Apoptosis. Death receptor signaling. Mitochondrial control of apoptosis.
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Chromatin regulation
Chormatin regualtion: Histone Lysine Methylation. Protein Acetylation. Examples of crosstalk between post-translational modifications.
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Histone methylation
Histones have been shown to be dynamic proteins, undergoing multiple types of post-translational modifications. In this pathway presented by Cell signaling you […]
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MAPK
The MAPK (mitogen-activated protein kinase) cascades are conserved signalling pathways that convert extracellular signals into cellular responses such as proliferation, differentiation, stress […]
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TGF-beta
The TGF-beta 1 (Transforming growth factor beta) is the first member of a large group of proteins included in the TGF-beta superfamily. […]
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PI3K/Akt
The PI3K/Akt pathway is a central regulator of cell growth, survival, metabolism and proliferation. It is one of the most frequently dysregulated […]
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Transcription factor Tubby
Transcription factor Tubby. You can use this tool clicking here