Other Tools

Other Tools

Simple Interactive Statistical Analysis

Biostatistics

After the procedure selection and fill in the form by the user, Simple Interactive Statistical Analysis (SISA) analyzes statistically the provided data. SISA also provides a friendly user guide to helps in the statistical test choice.

Structure Search

Other Tools

Structure Search is a research online tool presented by Sigma that allows the user to search for structures containing identical stereochemistry to the query structure.

Antibiotic selector

Other Tools

The Antibiotic Selector enables researchers to find quickly established antibiotic information. In this online tool, you will find about 200 antibiotics for contamination prevention, genetic marker selection and cell biology studies, while you obtain a summary of the application information, activity spectrum, solution stability, mode of action, and usage data.

MAPK

Pathways

Mitogen-activated protein kinases (MAPK) are a family of protein kinases involved in cell proliferation, cell differentiation, cell movement, and cell death. MAPK signaling cascades are organized hierarchically where: -MAPKs are phosphorylated and activated by MAPK-kinases (MAPKKs), -MAPKKs are phosphorylated and activated by MAPKK-kinases (MAPKKKs). -MAPKKKs are in turn activated by interaction with the family of …

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TGF-beta

Pathways

The TGF-beta 1 (Transforming growth factor beta) is the first member of a large group of proteins included in the TGF-beta superfamily. This superfamily includes the activin/inhibin family, bone morphogenetic proteins (BMPs), growth differentiation factors (GDFs) and the TGF-beta subfamily. Members of the TGF-beta superfamily interact with cell surface protein kinase receptors to activate Smad …

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PI3K/Akt

Pathways

The Akt cascade works through receptor tyrosine kinases, integrins, B and T cell receptors, cytokine receptors, G protein coupled receptors and other stimuli that induce the production of phosphatidylinositol 3,4,5 triphosphates (PtdIns(3,4,5)P3) by phosphoinositide 3-kinase (PI3K). There are three highly related isoforms of Akt (Akt1, Akt2, and Akt3), being the major signaling arm of PI3K.